Bonnie Klimes-Dougan, PhD

Professor, Department of Psychology

Bonnie Klimes-Dougan

Contact Info

klimes@umn.edu

Office Address:
Dept of Psychology
N412 Elliott Hall
75 E River Rd

Professor, Department of Psychology

Center for Neurobehavioral Development


Doctoral Degree, Florida State University (Psychology), 1992

Summary

My long-term goal is to explicate risk factors associated with early stages of depression and suicidal risk in an effort to more effectively intervene. By adolescence, approximately 10 to 15% of the population will experience a clinical depression. Early onset depression tends to be accompanied by a more severe course of subsequent illness and is associated with considerable morbidity (e.g., suicidal behavior). Efforts to target children at risk for depression, prior to or early on in the disease process are thought to be favorable approaches to facilitating adaptation and minimizing risk. To this end, my work has utilized developmental and neuroscience approaches that examine the stress/emotion regulatory systems implicated in depression. Recent work has focused on systems known to be critical to emotion/stress regulation including the assessment of key front-limbic neurocircuitry (e.g., using imaging techniques) and associated physiological (e.g., HPA axis) systems. A second theme of my research pertains to identifying factors that potentially modify these risk trajectories and have the potential to influence neurobiological regulatory processes that are disrupted in depressed youth (e.g., parenting emotion socialization practices, psychosocial prevention efforts).

Research

Publications

  • Klimes-Dougan, Bonnie, Klimes-Dougan, B., Eberly, L.E., Schreiner, M.W., Kurkiewicz, P., Houri, A., Schlesinger, A., Thomas, K.M., Mueller, B.A., Lim, K.O., & Cullen, K.R. (in press). Multilevel assessment of the neurobiological threat system in depressed adolescents: Interplay between the limbic system and HPA axis. . Development and Psychopathology
  • Cullen, K.R., Westlund, M., Klimes-Dougan, B., Houri, A., Mueller, B.A., Houri, A., Eberly, L.E., & Lim, K.O. (2014). Abnormal amygdala resting-state functional connectivity in adolescent depression. . Journal of the American Medical Association: Psychiatry.
  • Klimes-Dougan, B., Lee, C-Y.S. & Houri, A.K. in collaboration with SAVE (2009). Suicide prevention in adolescence: Considering potential benefits and untoward effects of public service announcements.. Crisis: Journal of Crisis Intervention and Suicide Prevention, 30, 128-135.
  • Cullen, K.R., Klimes-Dougan, B., Muetzel, R., Mueller, B.A., Camchong, J., Houri, A., Kumra, S., & Lim, K.O. (in press). Altered white matter microstructure in adolescent with major depression: A preliminary study. American Academy of Child and Adolescent Psychiatry
  • Cullen, K.R., Gee., D.G., Klimes-Dougan, B., Gabbay, V., Hulvershorn, L., Mueller, B.A., Camchong, J., Bell, C.J., Kumra, S., Lim, K.O., Casellanos, F.X., & Milham, M.P. (2009). A preliminary study of functional connectivity in comorbid adolescent depression. Neuroreport, 460, 227-231.
  • Klimes-Dougan, B., August, G.J., Lee, C-Y.S., Realmuto, G.M., Bloomquist, M.L., Horowitz, J.L., & Eisenberg, T. (in press). Practitioner and site characteristics that relate to fidelity of implementation: Early Risers prevention program in a going-to-scale intervention trial. Professional Psychology: Research and Practice
  • Hastings, P., Nuselovici, J.N., Klimes-Dougan, B., Kendziora, K.T., Usher, B., Ho, R., & Zahn-Waxler, C. (2009). Dysregulated coherence of subjective and cardic emotional activation in adolescents with internalizing and externalizing problems. Journal of Child and Adolescent Psychology and Psychiatry
  • Natsuaki, M.N., Klimes-Dougan, B., Ge, X., Shirtcliff, E.A., Hastings, P., & Zahn-Waxler, C. (2009). Early pubertal maturation and internalizing problems: The mediating role of cortisol reactivity to social stress. Jounal of Clinical Child Psychology